The stock of X4 Pharmaceuticals, Inc. (XFOR) plunged in the current market today. The stock lost more than 30% to trade at $2.67. At the end of the last trading session, the stock closed at $3.83. The average volume of the stock traded in the last trading session was around 346.84K.
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Reason of the stock decline:
There is no specific reason for the stock loss. In fact the company today in a press release announced a major development and presented New Clinical and Scientific Data at 2021 ASH Annual Meeting. That supports the broader potential for Mavorixafor in the treatment of Primary Immuno-deficiencies.
The oral use of Mavorixafor that is a CXCR4 adversary increases Peripheral White Blood Cell numbers in all various disease conditions. The effectiveness Mavorixafor has been observed with short-term and as well as long-term treatment in both solely or a blend with other therapies. These results shows that Mavorixafor has the potential to decrease the familiarity and/or seriousness of a broader array of immune-deficiencies than previously recognized, regardless of the presence or absence of CXCR4 mutations.
Sustained improvements were continuously shown by Mavorixafor in infection. In the ongoing study it has been observed to be well tolerated in WHIM syndrome Phase 2 open-label extension trial. The 52 week phase 3 clinical results are expected in the 4rth quarter of 2022.
A detailed development was observed in Vitro Characterization of CXCR4 WHIM Variants to decode the Genotype–Phenotype connection in WHIM Syndrome. For the prediction of CXCR4 variant pathogenicity in vitro and potentially as in vitro WHIM-related disease biomarkers, the data from the study shows that CXCR4 internalization and AKT activation may be used as key assays. CXCR4 variant cell lines were all tested to be sensitive to Mavorixafor at clinically required dosage.
Effect on the stock:
The stock lost more than 30% in the value. There must be some external reasons for the decline which could not be clear at the moment. As soon as the situation settles, the stock of the company may regain its value.
Conclusion:
The company is looking forward to the major development made in the recent study. This will play a key role in the sales of Mavorixafor for the treatment of primary immune-deficiencies.
